Cytoreductive Surgery and Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis

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Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy in peritoneal carcinomatosis.

BACKGROUND Peritoneal carcinomatosis is an advanced form of cancer with poor prognosis that in the past was treated mainly palliatively. Today, the definitive approach to peritoneal surface malignancy involves peritonectomy, visceral resection and perioperative intra-abdominal hyperthermic chemotherapy. The anticipated results range from at least palliative to as far as intent to cure. Proper p...

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Mortality and Morbidity after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis

Background: Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with improved survival in selected patients with peritoneal carcinomatosis. This treatment, however, has been associated with a relatively high rate of perioperative mortality and morbidity. Method: A review of clinical studies before March 2013 was performed to examine the impa...

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Clinical course for patients with peritoneal carcinomatosis excluded from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

BACKGROUND Cytoreductive surgery combined with 'Hyperthermic IntraPEritoneal Chemotherapy' (HIPEC) represents the only potentially curative treatment available for carcinomatosis secondary to colorectal cancer (CRC), pseudomyxoma peritonei (PMP), malignant peritoneal mesothelioma (MM) and goblet cell carcinoma (GCC). Despite preoperative investigation some patients are excluded perioperatively ...

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Peritoneal carcinomatosis of colorectal origin Is there a role for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy?

Siham Zerhouni, MD is a surgical resident with the Department of Surgery, University of British Columbia, Vancouver, and a graduate student in the Division of Experimental Therapeutics, Toronto General Research Institute and Institute of Medical Science, University of Toronto. J. Andrea McCart, MD, MSc, FRCSC is the Director of the Ontario Peritoneal Malignancy Program; associate Professor in t...

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Combined Cytoreductive Surgery and Early Postoperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis of Gastric Cancer.

PURPOSE Peritoneal seeding is the most common type of metastasis or recurrence and one of the poor prognostic factors in gastric cancer. Moreover, there are as yet no effective treatment modalities available. Recently some research groups suggested the benefit of combined cytoreductive surgery and intraperitoneal chemotherapy, but the related experiments remain in the trial stage. Therefore, we...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1995

ISSN: 0003-4932

DOI: 10.1097/00000658-199502000-00001